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Prof. Dr. Markus Pietsch
Kontaktdaten
E-Mail:
markus.pietsch@th-koeln.de
Webseite:
Publikationen:
Als Autor*in:
- A CK2α′ Mutant Indicating Why CK2α and CK2α′, the Isoforms of the Catalytic Subunit of Human Protein Kinase CK2, Deviate in Affinity to CK2β
- Contilisant-Belinostat Hybrids: Polyfunctionalized Indole Derivatives as Multineurotarget Drugs for the Potential Treatment of Alzheimer’s Disease
- HTA161 German Early Benefit Assessments and the Impact of Medical Societies
- In-depth Analysis of Gαs Protein Activity by Probing Different Fluorescently Labeled Guanine Nucleotides
- Photodecarboxylative Ring Annulation of α- and β-Functionalized Phthaloyl-GABA Derivatives
- Structure–Activity Relationship Studies of Tetracyclic Pyrrolocarbazoles Inhibiting Heterotetrameric Protein Kinase CK2
- Synthesis and Evaluation of Radioiodinated Estrogens for Diagnosis and Therapy of Male Urogenital Tumours
- The Impact of Nε-Acryloyllysine Piperazides on the Conformational Dynamics of Transglutaminase 2
- Angiotensin II Type 1 Receptor Localizes at the Blood–bile Barrier in Humans and Pigs
- Application of a Fluorescence Anisotropy-Based Assay to Quantify Transglutaminase 2 Activity in Cell Lysates
- Fluorescence Anisotropy Assay with Guanine Nucleotides Provides Access to Functional Analysis of Gαi1 Proteins
- 2-Substituted Thienotetrahydropyridine Derivatives: Allosteric Ectonucleotidase Inhibitors
- Development of an ¹⁸F-Labeled Irreversible Inhibitor of Transglutaminase 2 as Radiometric Tool for Quantitative Expression Profiling in Cells and Tissues
- Distinct 3-disulfide-bonded Isomers of Tridegin Differentially Inhibit Coagulation Factor XIIIa: The Influence of Structural Stability on Bioactivity
- Solution-phase Synthesis of the Fluorogenic TGase 2 Acyl Donor Z-Glu(HMC)-Gly-OH and its use for Inhibitor and Amine Substrate Characterisation
- Synthesis and SAR of Tetracyclic Inhibitors of Protein Kinase CK2 Derived from Furocarbazole W16
- Unexpected CK2β-antagonistic Functionality of Bisubstrate Inhibitors Targeting Protein Kinase CK2
- ω-Quinazolinonylalkyl Aryl Ureas as Reversible Inhibitors of Monoacylglycerol Lipase
- Chromenones as Multineurotargeting Inhibitors of Human Enzymes
- Design of CK2β-Mimicking Peptides as Tools To Study the CK2α/CK2β Interaction in Cancer Cells
- Direct, Gabapentin-insensitive Interaction of a Soluble Form of the Calcium Channel Subunit α2δ-1 with Thrombospondin-4
- Characterization of Fatty Acid Amide Hydrolase Activity by a Fluorescence-based Assay
- Crystal Structure of Highly Glycosylated Human Leukocyte Elastase in Complex with an S200 Site Binding Inhibitor
- Nϵ-Acryloyllysine Piperazides as Irreversible Inhibitors of Transglutaminase 2
- ω-Phthalimidoalkyl Aryl Ureas as Potent and Selective Inhibitors of Cholesterol Esterase
- Assessment of Inhibitory Effects on Major Human Cytochrome P450 Enzymes by Spasmolytics used in the Treatment of Overactive Bladder Syndrome
- A Lluorescence Anisotropy-Based Assay for Determining the Activity of Tissue Transglutaminase
- Synthesis and Kinetic Characterisation of Water-Soluble Fluorogenic Acyl Donors for Transglutaminase 2
- Activated Microglia/Macrophage whey Acidic Protein (AMWAP) Inhibits NFΚB Signaling and Induces a Neuroprotective Phenotype in Microglia
- Model Studies on Peroxidic Glutathione Transferase (GST) Inhibitors: C5-Methylated 1,2,4-Trioxanes with C6-Acrylate Side Chains
- Selective Inhibitors of Glutathione Transferase P1 with Trioxane Structure as Anticancer Agents
- Development of a High-throughput screening-compatible Assay to Identify Inhibitors of the CK2α/CK2β Interaction
- Macrocyclic Protease Inhibitors with Reduced Peptide Character
- First Structure of Protein Kinase CK2 Catalytic Subunit with an Effective CK2β-Competitive Ligand
- Regioselective Sulfonylation and N- to O-Sulfonyl Migration of Quinazolin-4(3H)-ones and Analogous Thienopyrimidin-4(3H)-ones
- Synthesis and Extended Activity of Triazole‐Containing Macrocyclic Protease Inhibitors
- Tissue Transglutaminase
- New Cholesterol Esterase Inhibitors Based on Rhodanine and Thiazolidinedione Scaffolds
- Calpains: Attractive Targets for the Development of Synthetic Inhibitors
- Fluorinated β²- and β³-Amino Acids: Synthesis and Inhibition of α-Chymotrypsin
- Isopropylammonium Tetrafluorohydrogenphthalate
- Kinetics of Inhibition of Acetylcholinesterase in the Presence of Acetonitrile
- Multiple Ligands in Opioid Research
- Structural Characterization of Two Salts Derived from Tetrafluorophthalic Acid and Isopropylamine
- N-Benzyltetrahydropyrido-Anellated Thiophene Derivatives: New Anticholinesterases
- Compatible Solutes as Protectants for Zymogens against Proteolysis
- 2,4,5-Triphenylisothiazol-3(2H)-one 1,1-Dioxides as Inhibitors of Human Leukocyte Elastase
- Cholesterol Esterase Action on Human High Density Lipoproteins and Inhibition Studies
- Synthesis of Tricyclic 1,3-Oxazin-4-ones and Kinetic Analysis of Cholesterol Esterase and Acetylcholinesterase Inhibition
- Synthesis of 2-Phenylisothiazol-3(2H)-one 1,1-Dioxides: Inhibitors of Human Leukocyte Elastase
- Alternate Substrate Inhibition of Cholesterol Esterase by Thieno[2,3-d][1,3]oxazin-4-ones
- Inhibition of Cathepsin G by 2-Amino-3,1-Benzoxazin-4-ones: Kinetic Investigations and Docking Studies
- 2-(Diethylamino)thieno[1,3]Oxazin-4-ones as Stable Inhibitors of Human Leukocyte Elastase
Publikationsliste
Publikationsliste (CSV)
Publikationsliste (PDF) im "American Psychological Association 6th edition (DOI)"-Zitierstil
Publikationsliste (PDF) im "Anglia Ruskin University - Harvard"-Zitierstil
Publikationsliste (PDF) im "Gesellschaft für Bildung und Forschung in Europa - Harvard"-Zitierstil
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Als Autor*in::
- A CK2α′ Mutant Indicating Why CK2α and CK2α′, the Isoforms of the Catalytic Subunit of Human Protein Kinase CK2, Deviate in Affinity to CK2β
- Contilisant-Belinostat Hybrids: Polyfunctionalized Indole Derivatives as Multineurotarget Drugs for the Potential Treatment of Alzheimer’s Disease
- HTA161 German Early Benefit Assessments and the Impact of Medical Societies
- In-depth Analysis of Gαs Protein Activity by Probing Different Fluorescently Labeled Guanine Nucleotides
- Photodecarboxylative Ring Annulation of α- and β-Functionalized Phthaloyl-GABA Derivatives
- Structure–Activity Relationship Studies of Tetracyclic Pyrrolocarbazoles Inhibiting Heterotetrameric Protein Kinase CK2
- Synthesis and Evaluation of Radioiodinated Estrogens for Diagnosis and Therapy of Male Urogenital Tumours
- The Impact of Nε-Acryloyllysine Piperazides on the Conformational Dynamics of Transglutaminase 2
- Angiotensin II Type 1 Receptor Localizes at the Blood–bile Barrier in Humans and Pigs
- Application of a Fluorescence Anisotropy-Based Assay to Quantify Transglutaminase 2 Activity in Cell Lysates
- Fluorescence Anisotropy Assay with Guanine Nucleotides Provides Access to Functional Analysis of Gαi1 Proteins
- 2-Substituted Thienotetrahydropyridine Derivatives: Allosteric Ectonucleotidase Inhibitors
- Development of an ¹⁸F-Labeled Irreversible Inhibitor of Transglutaminase 2 as Radiometric Tool for Quantitative Expression Profiling in Cells and Tissues
- Distinct 3-disulfide-bonded Isomers of Tridegin Differentially Inhibit Coagulation Factor XIIIa: The Influence of Structural Stability on Bioactivity
- Solution-phase Synthesis of the Fluorogenic TGase 2 Acyl Donor Z-Glu(HMC)-Gly-OH and its use for Inhibitor and Amine Substrate Characterisation
- Synthesis and SAR of Tetracyclic Inhibitors of Protein Kinase CK2 Derived from Furocarbazole W16
- Unexpected CK2β-antagonistic Functionality of Bisubstrate Inhibitors Targeting Protein Kinase CK2
- ω-Quinazolinonylalkyl Aryl Ureas as Reversible Inhibitors of Monoacylglycerol Lipase
- Chromenones as Multineurotargeting Inhibitors of Human Enzymes
- Design of CK2β-Mimicking Peptides as Tools To Study the CK2α/CK2β Interaction in Cancer Cells
- Direct, Gabapentin-insensitive Interaction of a Soluble Form of the Calcium Channel Subunit α2δ-1 with Thrombospondin-4
- Characterization of Fatty Acid Amide Hydrolase Activity by a Fluorescence-based Assay
- Crystal Structure of Highly Glycosylated Human Leukocyte Elastase in Complex with an S200 Site Binding Inhibitor
- Nϵ-Acryloyllysine Piperazides as Irreversible Inhibitors of Transglutaminase 2
- ω-Phthalimidoalkyl Aryl Ureas as Potent and Selective Inhibitors of Cholesterol Esterase
- Assessment of Inhibitory Effects on Major Human Cytochrome P450 Enzymes by Spasmolytics used in the Treatment of Overactive Bladder Syndrome
- A Lluorescence Anisotropy-Based Assay for Determining the Activity of Tissue Transglutaminase
- Synthesis and Kinetic Characterisation of Water-Soluble Fluorogenic Acyl Donors for Transglutaminase 2
- Activated Microglia/Macrophage whey Acidic Protein (AMWAP) Inhibits NFΚB Signaling and Induces a Neuroprotective Phenotype in Microglia
- Model Studies on Peroxidic Glutathione Transferase (GST) Inhibitors: C5-Methylated 1,2,4-Trioxanes with C6-Acrylate Side Chains
- Selective Inhibitors of Glutathione Transferase P1 with Trioxane Structure as Anticancer Agents
- Development of a High-throughput screening-compatible Assay to Identify Inhibitors of the CK2α/CK2β Interaction
- Macrocyclic Protease Inhibitors with Reduced Peptide Character
- First Structure of Protein Kinase CK2 Catalytic Subunit with an Effective CK2β-Competitive Ligand
- Regioselective Sulfonylation and N- to O-Sulfonyl Migration of Quinazolin-4(3H)-ones and Analogous Thienopyrimidin-4(3H)-ones
- Synthesis and Extended Activity of Triazole‐Containing Macrocyclic Protease Inhibitors
- Tissue Transglutaminase
- New Cholesterol Esterase Inhibitors Based on Rhodanine and Thiazolidinedione Scaffolds
- Calpains: Attractive Targets for the Development of Synthetic Inhibitors
- Fluorinated β²- and β³-Amino Acids: Synthesis and Inhibition of α-Chymotrypsin
- Isopropylammonium Tetrafluorohydrogenphthalate
- Kinetics of Inhibition of Acetylcholinesterase in the Presence of Acetonitrile
- Multiple Ligands in Opioid Research
- Structural Characterization of Two Salts Derived from Tetrafluorophthalic Acid and Isopropylamine
- N-Benzyltetrahydropyrido-Anellated Thiophene Derivatives: New Anticholinesterases
- Compatible Solutes as Protectants for Zymogens against Proteolysis
- 2,4,5-Triphenylisothiazol-3(2H)-one 1,1-Dioxides as Inhibitors of Human Leukocyte Elastase
- Cholesterol Esterase Action on Human High Density Lipoproteins and Inhibition Studies
- Synthesis of Tricyclic 1,3-Oxazin-4-ones and Kinetic Analysis of Cholesterol Esterase and Acetylcholinesterase Inhibition
- Synthesis of 2-Phenylisothiazol-3(2H)-one 1,1-Dioxides: Inhibitors of Human Leukocyte Elastase
- Alternate Substrate Inhibition of Cholesterol Esterase by Thieno[2,3-d][1,3]oxazin-4-ones
- Inhibition of Cathepsin G by 2-Amino-3,1-Benzoxazin-4-ones: Kinetic Investigations and Docking Studies
- 2-(Diethylamino)thieno[1,3]Oxazin-4-ones as Stable Inhibitors of Human Leukocyte Elastase
Publikationsliste
Publikationsliste (CSV)
Publikationsliste (PDF) im "American Psychological Association 6th edition (DOI)"-Zitierstil
Publikationsliste (PDF) im "Anglia Ruskin University - Harvard"-Zitierstil
Publikationsliste (PDF) im "Gesellschaft für Bildung und Forschung in Europa - Harvard"-Zitierstil
Download
RDF/XML-Format
JSON-LD-Format
Turtle-Format
N3-Format